Some Hormonal Assay in Toxoplasma Infected University Students

Background: toxoplsma is a parasite with a global distribution that infect both human and animal, most of human toxoplasmosis is chronic infection. chronic toxoplasmosis can affect human behavioral and hormonal status. objective: in this study the effect of toxoplasmosis on the level of certain hormones (total testosterone, estradiol (e2), follicle stimulating hormone (fsh) have been investigated. methods: one hundred and ninety serum samples from kirkuk university students were assayed for toxoplasma antibody (igm,igg), among them 40 (21.1%) samples were positive the serum of positive samples along with control group were assayed for some hormonal levels by using elis technique. results: from the obtained results after conducting statistical analysis, it has been found that there is a significant differences in testosterone and estradiol concentration in both infected males and females comparing with the uninfected control cohort. the concentration range of testosterone were (12.8-15.5, 1.6-3.1 ng/ml) for each of infected male and female respectively which was significantly higher than the control (6.9-8.0,0.39-o.58 ng/ml) respectively for male and female. the estradiol concentration range in infected cohort were (34.3-39.6, 184.3-197.0 pg/ml) for male and female respectively, comparing with the control (22.2-26.9, 72.8-75.5 pg/ml) for male and female respectively. no significant differences were appeared between the fsh concentrations in infected and control cohort in both male and female. the infected males were a little taller and more depressed than uninfected one. conclusions: from the current study we concluded that chronic toxoplasmosis can affect some hormonal concentration in human blood which may change or influence human behavior.