The Reactivity of Anti-HCMV IgM to Various Specific HCMV Antigens Among Pregnant Women in Kirkuk.

Human cytomegalovirus (hcmv) is a dna virus of the betaherpesvirinae subfamily and herpesviridae family. hcmv is a leading cause of congenital infections throughout the world. this study was carried out in kirkuk governorate from july 2017 to january 2018,aimed at studying there activity of anti-hcmv igm to various specific hcmv antigens among 180 pregnant women attending hospitals, primary health care centers and some private medical laboratories. the pregnant women were examined for hcmv-igm seroprevalence using electro-chemo-luminescence(eclia) technique then examined their reactivity for specific hcmv antigens using line immune assay. the rates of hcmv-igm seropositive were 22 (12.22 %). regarding the reactivity of determined hcmv-igm against various hcmv antigens, the rates 14 (63.63%), 13(59.09%), 21(95.45%), 15(68.18%), 21(95.45%) and 16(72.72%) were seropositive for hcmv ie1, cm2, p150, p65, gb1 and gb2 antigens, respectively. concerning the band intensity of hcmv-igm reactions with hcmv antigens, the rates of (+++) were higher than other band intensity for all antigens with highest rate for gb1 antigen (85.71%). so, the highest rate of hcmv-igm reaction with the number of antigens was 40.90% for three antigens at the same time. in conclusion, the highest rate of hcmv-igm in pregnant women was for gb1and p150 antigens; while the highest rate of intensity reaction was (+++)and the highest rate of hcmv-igm ability for reaction was for three antigens at the same time.