Determination of Some Biochemical Parameters of Patients with Hepatitis B in Kirkuk City

Hepatitis b infection is a worldwide healthcare problem, especially in developing areas. the current study was to evaluate the alterations in different biochemical parameters including paraoxonase (pon), 5′-nucleotidase (5nt), total bilirubin, direct bilirubin, indirect bilirubin, prothrombin time (pt), alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), total serum protein (tsp), albumin (alb), superoxide dismutase (sod) and ɣ-glutamyl transpeptidase (ggt) in the serum samples of the viral hepatitis patients (n=100) compared with healthy controls(n=100). this study shown that there were significant increase (p<0.05) in the tsb, d. bilirubin, in. bilirubin, ast, alt, pt, ggt, 5-nt, and alp in viral hepatitis patients compared to their respective normal controls and there were significant decrease (p<0.05) in the serum (pon, sod) activities, tsp and albumin concentration. it can be concluded that pon, 5-nt, sod, alt, ast, alp and ggt may be specific method for making a diagnosis of viral hepatitis and also in distinguishing it with other kinds of hepatitis.