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Synthesis, Characterization and Biological Activity Evaluation of Some New Azo Derivatives from 2- Amino Benzothiazole and Their Derivatives
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نویسنده
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hassan husain f. ,barzinji abdul kadir r. a.
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منبع
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kirkuk university journal: scientific studies - 2018 - دوره : 13 - شماره : 1 - صفحه:212 -227
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چکیده
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This study includes synthesis 2-amino benzothiazole and its substitutes (m1-m14) by the reaction of aniline derivatives with kscn in presence of br2 and glacial acetic acid then neutralize by concentrated ammonia solution or (by 50% naoh). the prepared compounds (m3-m5-m6-m11) were used for preparation diazonium salts through reaction with nano2 and hcl, at that point diazonium salts were utilized specifically interaction with 4-amino antipyrine and 4-amino-3-hydroxy-1-naphthalene sulphonic acid (in alkaline medium) to produce azo dyes (m15-m22). these compounds were characterized by their physical properties, spectroscopic information (ft-ir, 1h-nmr, 13c-nmr and chns elemental analysis), and also to systematically defining of a few active functional groups for these prepared compounds. the biological activity evaluated for four of prepared compounds towards four kinds of bacteria .
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کلیدواژه
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azo dyes ,diazonium salts ,benzothiazole ,4-amino antipyrine
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آدرس
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kirkuk university, college of science, biology department, Iraq, university of kirkuk, college of educational-hawija, biology department, Iraq
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پست الکترونیکی
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gaylan_phd2@yahoo.com
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Authors
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