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smart on-demand and programmed injectable gels for cancer treatment
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نویسنده
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salehi saba ,naghib morteza
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منبع
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multidisciplinary cancer investigation - 2023 - دوره : 7 - شماره : 1 - صفحه:1 -10
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چکیده
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Hydrogels are often exploited biological materials in the transfer of biomolecules such as medications, dna, and proteins owing to apparent features, including cytocompatibility and likeness to genuine human tissues. a number of biomaterials have the capacity to be injected, which allows for minimum invasion and eliminates the necessity of surgery to transplant pre-formed materials. this material is injected through the target location in a solution condition before gelling. if a stimulus generates gelation by the interaction of one or more stimuli, it can do so spontaneously. when such occurs, the material/system is referred to be stimuli-responsive since it reacts to its environment. in this context, we discussed the many triggers leading to gelation and reviewed the various processes by which the solution becomes a gel. we also reviewed several trials that used these gels to treat cancer. these materials show promise for treating cancer. injectable hydrogels and stimuli-sensitive materials were the topics of several studies and reviews. to our knowledge, there has not been any research done on the use of smart injectable hydrogels for tumor therapy.
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کلیدواژه
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injectable ,stimuli responsive polymers ,drug delivery systems ,neoplasms ,therapeutic
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آدرس
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iran university of science and technology (iust), school of advanced technologies, nanotechnology department, iran, iran university of science and technology (iust), school of advanced technologies, nanotechnology department, iran
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پست الکترونیکی
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naghib@iust.ac.ir
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Authors
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