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pyoderma gangrenosum-like ulcers associated granulomatosis with polyangiitis
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نویسنده
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avila katia fabiola ,lópez karla ,muñoz maría del coral durand ,cherit judith guadalupe domínguez
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منبع
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case reports in clinical practice - 2024 - دوره : 9 - شماره : 1 - صفحه:6 -9
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چکیده
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Granulomatosis with polyangiitis is an anca-positive vasculitis primarily affecting small to medium-sized vessels, typically involving the lungs and kidneys. this article presents a remarkable case of a patient with an unusual pyoderma gangrenosum-like ulcer on the face and granulomatosis with polyangiitis. a 28-year-old man, previously diagnosed with granulomatosis with polyangiitis presented at a dermatology clinic with a 6-month-old ulcer in the right preauricular region following a traumatic incident. a spindle biopsy revealed suppurative granulomatous dermatitis with secondary vascular damage, while cultures showed no signs of infection. the patient was subsequently treated with rituximab, leading to a positive clinical response. this case underscores the challenge of diagnosing this rare manifestation of granulomatosis with polyangiitis and suggests that rituximab could be a valuable treatment option.
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کلیدواژه
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granulomatosis; polyangiitis; pyoderma; gangrenosum; rituximab; vasculitis
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آدرس
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instituto nacional de ciencias médicas y nutrición salvador zubirán, mexico, instituto nacional de ciencias médicas y nutrición salvador zubirán, mexico, instituto nacional de ciencias médicas y nutrición salvador zubirán, mexico, instituto nacional de ciencias médicas y nutrición salvador zubirán, mexico
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پست الکترونیکی
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dominguez.judith@gmail.com
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Authors
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