A Rare Case of Acute Myeloblastc Leukemia With Blast Count Less Than 20% in Bone Marrow

One of the diagnostic criteria for acute myeloblastic leukemia (aml) is the presence of 20% myeloid blasts in peripheral blood or bone marrow. some cases with recurrent cytogenetic abnormalities also fall in this category with blast cell count less than 20%. thus, in the presence of these genetic abnormalities, the patients are classified as aml regardless of blast cell count. one of these genetic heterogeneities is t(8; 21) (q22, q22.1) which is more commonly seen in children and young adults. in this study, a 14yearold boy is reported with a final diagnosis of aml, which was presented with fever and bicytopenia, clinically suspicious for acute leukemia. laboratory results reported less than 20% blasts in bone marrow aspiration smears but genetic alteration t(8; 21) (q22, q22.1) was detected by molecular exams.