polycystic ovary syndrome combined with type ii polyglandular autoimmune syndrome

A 30-year-old woman with a 20-year history of type 1 diabetes referred to our clinic with the complaints of facial acne, hirsutism, and irregular menstrual cycles (hirsutism was identified in physical examination). on biochemical analysis, high serum levels of anti- tpo and dhea-s were detected. based on ultrasonographic findings indicative of thyroiditis and positive anti-tpo test, the diagnosis of hashimoto's thyroiditis was made. a diagnosis of polycystic ovary syndrome (pcos) was confirmed later according to the rotterdam criteria (revised 2003). the patient received metformin and insulin for 3 months and her menstrual cycles became regular.