coexisting pituitary adenoma and suprasellar meningioma: a coincidence or causation effect? report of two cases and review of literature

Background and importance:the coexistence of pituitary adenoma and another type of brain tumor is a very rare clinical scenario. even though such a presentation can be an incidental event but the possible pathogenesis of coexistence of different lesions in the sella and suprasellar region has not yet been elucidated. case presentation: two cases of concomitant sellar and suprasellar region tumors are reported. a 37-year-old lady with prolactinoma and a suprasellar meningioma and a 42-year-old acromegalic man with suprasellar meningioma and a pituitary adenoma (pa). conclusion both meningiomas were removed transcranially while the prolactinoma could be managed medically and the growth hormone (gh) secreting adenoma was removed trans-sphenoidally. the visual problems and hormonal imbalances of both patients improved postoperatively and there has been no sign of recurrence of the lesions after a mean of five years follow up. the literature is reviewed on this topic and the possible pathogenesis and management protocol of similar lesions are discussed.