multifocal intradural extramedullary anaplastic ependymoma with intracranial involvement at presentation: a case report

Background and importance: ependymomas are a rare malignant neoplasm. multifocalintradural extramedullary anaplastic ependymomas are even more of a rare entity withmuch of the current knowledge derived from case reports. we presented a case of amultifocal intradural extramedullary anaplastic ependymoma with intracranial involvementat presentation.case presentation: a 53-year-old male presented with urinary symptoms. magneticresonance imaging revealed two lesions along the spinal cord and two lesions, intracranially.histopathological examination was consistent with the world health organization grade iiianaplastic ependymoma. the patient was treated with the gross total resections of spinalcord lesions, followed by radiation therapy to the resection cavities and intracranial lesions.at the 10-month follow-up visit, he reported almost complete resolution of symptoms, andmagnetic resonance imaging revealed no recurrence.conclusion: despite their rarity, ependymomas should be considered as the differentialdiagnosis when evaluating spinal tumors. gross total resection followed by targetedradiotherapy appears to be an effective treatment modality for high-grade lesions.