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   correlation between initial lung involvement on ct scan, assessed by total severity score, and pulmonary outcomes after three months in patients with severe covid-19  
   
نویسنده bozorgmehr rama ,hooshmand zahra ,changizi faraz ,khameneh bagheri arash ,khoshravesh sahar
منبع journal of cellular and molecular anesthesia - 2024 - دوره : 9 - شماره : 4 - صفحه:1 -11
چکیده    background: patients with severe covid-19 experience various respiratory complications, which can have potential long-termeffects.objectives: this study investigates the long-term pulmonary consequences of severe covid-19 and their relationship with theseverity of lung involvement.methods: all patients who survived severe covid-19 in the icu were selected for the study. a radiologist reviewed the chest ctscans, and patients were categorized based on their total severity score (tss) into two groups: group a (tss ≤ 7) and group b (tss> 7). patients were followed up after three months with a chest ct scan, spirometry, spo2 measurement, and a dyspnea scoreassessment.results: the mean age was 54.69 ± 12.51 for group a and 55.31 ± 12.73 for group b. groups a and b had 23 (46.9%) and 39 (39.4%)female patients, respectively. patients in group b had significantly lower spo2 and a prolonged length of hospitalization. groupb also experienced more severe dyspnea and reduced lung function, as observed in spirometry during the three-month followup. the total severity score decreased significantly after three months in all patients (from 14.42 ± 5.90 to 6.68 ± 4.79; p < 0.001). after logistic regression analysis, non-invasive ventilation was independently associated with a higher tss (or = 0.45 when comparing group a to group b; p = 0.028).conclusions: the lungs are the most affected organ by covid-19, making it crucial to investigate the effects of the virus on pulmonary function. our study showed that patients with higher tss experienced greater reductions in lung function during the three-month follow-up. additionally, the use of non-invasive ventilation was independently associated with a higher tss in severe covid-19 cases.
کلیدواژه covid-19 ,severe covid-19 ,tss ,lung involvement ,pulmonary outcomes
آدرس shahid beheshti university of medical sciences, clinical research development unit, shohada-e tajrish hospital, iran, shahid beheshti university of medical sciences, clinical research development unit, shohada-e tajrish hospital, iran, shahid beheshti university of medical sciences, school of medicine, iran, shahid beheshti university of medical sciences, shohadaye tajrish hospital, iran, shahid beheshti university of medical sciences, school of medicine, iran
پست الکترونیکی sahar.khshrvsh@gmail.com
 
     
   
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