Anesthetic Management in Tibial Fracture of a Known Case of Wolfram Syndrome

Wolfram syndrome is a rare progressive disease with diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (didmoad). furthermore, other comorbidities and manifestations accompany this disease. anesthetic management may be challenging in these cases and need special consideration due to present symptoms, disabilities, and comorbidities. this report presents anesthetic management of a traumatic patient with wolfram syndrome candidate for orthopedic surgery. the report also discusses manifestation and anesthetic consideration in this population.