|
|
|
|
The Spike Protein Mutations and its Effect on SARS-CoV-2 Pathogenesis
|
|
|
|
|
|
|
|
نویسنده
|
zandi milad ,soltani saber ,sanami samira ,rasooli azadeh
|
|
منبع
|
journal of cellular and molecular anesthesia - 2021 - دوره : 6 - شماره : 2 - صفحه:148 -153
|
|
چکیده
|
The severe acute respiratory syndrome coronavirus 2 spike (s) glycoprotein facilitates receptor binding to initiate cell entry that is the critical initial step in the infection cycle. due to s glycoprotein's pivotal role, in this review, we pointed to show potential functional and structural consequences of s glycoprotein and its variants, which has been related to increased viral load in humans with sars-cov-2 infection.
|
|
کلیدواژه
|
Spike glycoprotein; Mutation ,Macromolecule ,COVID-19 ,SARS-CoV-2
|
|
آدرس
|
tehran university of medical sciences, school of public health, research center for clinical virology, department of virology, Iran, tehran university of medical sciences, school of public health, research center for clinical virology, department of virology, Iran, shahrekord university of medical sciences, school of advanced technologies, department of medical biotechnology, Iran, payame noor university, faculty of sciences, department of biochemistry, Iran. pasteur institute of iran, virology department, Iran
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|