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the role of ketamine in calcium changes in intracellular homeostasis and mitochondrial dysfunction
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نویسنده
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legiran legiran ,irfannuddin irfannuddin ,ahmad ramli ,ibrahim nurhadi ,zainal rizal
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منبع
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journal of cellular and molecular anesthesia - 2024 - دوره : 9 - شماره : 2 - صفحه:1 -8
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چکیده
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Ketamine was formerly introduced as an anesthesia drug and known as a non-competitive antagonist of the n-methyl-d-aspartate receptor (nmdar). as knowledge grows, recent studies reveal the antidepressant effect of the drug. moreover, a few investigations indicate that ketamine might be responsible for multiple calcium-regulated signaling pathways. ketamine is thought to affect calcium homeostasis through several of its targets, such as n-methyl-d-aspartate (nmda), α-amino-3-hydroxy-5-methylisoxazole-4-propionate acid receptors (ampa), and voltage-dependent calcium channels (vdccs).
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کلیدواژه
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cellular ,ketamine ,n-methyl-d-aspartate (nmda) ,pain
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آدرس
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sriwijaya university, faculty of medicine, department of biomedicine, indonesia, sriwijaya university, faculty of medicine, department of physiology, indonesia, hasanuddin university, faculty of medicine, general hospital of wahidin sudirohusodo, department of anesthesiology and intensive care, indonesia, indonesia university, faculty of medicine, department of medical physiology, indonesia, sriwijaya university, faculty of medicine, department of biomedicine and department of anesthesiology and intensive care, indonesia
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پست الکترونیکی
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rizalprabu@gmail.com
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Authors
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