MATLAB-based sequence analysis of muRdr1H,a functionally characterized resistance gene of roses

One of the practical applications of bioin format ics is sequence analysis through sequence alignment of newly identified genes and previously available sequences to determine the similarity between the biological sequences and elucidate the functionality of genes with confidence. although there are many softwares available for the biological sequence alignment; in this paper some basic alignment algorithms are discussed and implemented in matlab bioinformatics tool box. two sequences analyzed by this tool box were murdrlh and resistance protein of populustrichocarpa (accession xp_002329162). murdrjh is a functionally characterized member of rdri resistance gene family of roses,active against black spot. the simulated result shows that the matlab tool is a comprehensive tool for finding best possible local and global sequence alignment. our proposed work provides useful application of matlab which can help in interpretation and visualization of the data in molecular biology. © pakistan academy of sciences.