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The role of PPAR activation in liver and muscle
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نویسنده
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burri l. ,thoresen g.h. ,berge r.k.
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منبع
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ppar research - 2010 - شماره : 0
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چکیده
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Ppar is one of three members of the soluble nuclear receptor family called peroxisome proliferator-activated receptor (ppar). it is a sensor for changes in levels of fatty acids and their derivatives that responds to ligand binding with ppar target gene transcription,inasmuch as it can influence physiological homeostasis,including lipid and carbohydrate metabolism in various tissues. in this paper we summarize the involvement of ppar in the metabolically active tissues liver and skeletal muscle and provide an overview of the risks and benefits of ligand activation of ppar,with particular consideration to interspecies differences. copyright © 2010 lena burri et al.
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آدرس
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institute of medicine,haukeland university hospital,university of bergen, Norway, department of pharmaceutical biosciences,school of pharmacy,university of oslo, Norway, institute of medicine,haukeland university hospital,university of bergen, Norway
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Authors
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