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Long-term mortality analysis in Parkinson's disease treated with deep brain stimulation
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نویسنده
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rocha s. ,monteiro a. ,linhares p. ,chamadoira c. ,basto m.a. ,reis c. ,sousa c. ,lima j. ,rosas m.j. ,massano j. ,vaz r.
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منبع
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parkinson's disease - 2014 - دوره : 2014 - شماره : 0
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چکیده
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Background. few data have been published regarding long-term mortality in patients with parkinson's disease treated with dbs. methods. this study analyzed long-term mortality rates,causes,and correlates in pd patients treated with dbs. results. 184 consecutive patients were included; mean follow-up was 50 months. fifteen deaths occurred (total 8.15%,annual mortality rate 1.94%). mean age at disease onset and at surgery was 48±2.4 and 63±1.6 years,respectively. mean disease duration until death was 21±7.8 years. most deaths related to stroke,myocardial infarction,other vascular/heart disorders,or severe infection; one suicide was recorded. deceased pd patients were mostly male and had lower motor benefit after dbs,but univariate analysis failed to show significant differences regarding gender and motor benefit. survival was 99% and 94% at 3 and 5 years. conclusions. long-term survival is to be expected in pd patients treated with dbs,possibly higher than previously expected. death usually supervenes due to vascular events or infection. © 2014 sofia rocha et al.
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آدرس
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department of neurology,hospital de braga,sete fontes,são victor,4710-243 braga,portugal,movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro,4200-319 porto,portugal,department of clinical neurosciences and mental health,faculty of medicine,university of porto,alameda prof. hernâni monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro,4200-319 porto,portugal,department of clinical neurosciences and mental health,faculty of medicine,university of porto,alameda prof. hernâni monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro,4200-319 porto,portugal,department of clinical neurosciences and mental health,faculty of medicine,university of porto,alameda prof. hernâni monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro,4200-319 porto,portugal,department of clinical neurosciences and mental health,faculty of medicine,university of porto,alameda prof. hernâni monteiro,4200-319 porto,portugal,department of neurology,hospital pedro hispano,uls matosinhos,rua dr. eduardo torres,senhora da hora, Portugal, movement disorders and functional surgery unit,centro hospitalar são joão,alameda prof. hernâi monteiro,4200-319 porto,portugal,department of clinical neurosciences and mental health,faculty of medicine,university of porto,alameda prof. hernâni monteiro, Portugal
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Authors
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