Helicobacter Pylori in Children: Newer Diagnostic Techniques and Treatment Strategies

Helicobacter pylori [h.p] infection is a newer infective organism of gastrointestinal system which not only is an asymptomatic infection in children but is now an established cause of peptic ulcer disease as well as a carcinogen. it is now incriminated in many other disorders. the diagnostic modalities have limitations in pediatric age group. our ever changing world mandates clinicians to be abreast and equipped with information to recognize,evaluate and be able to treat patients effectively. flexible endoscopy allows for direct visualization of the mucosa; for the detection of h pylori by means of biopsy,culture,cytological analysis and for dna testing through pcr. however,issues of availability,acceptance by parents,and cost certainly remain limiting factors. non invasive modalities are becoming more available,acceptable and affordable. eradication treatment in children is available with over 90% rate of success. eradication of hp is recommended for hp positive peptic ulcer disease. information about pediatric aspects of this infection and disease should increase awareness and appropriate diagnosis and management.