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   Anti irritant activity of extract from the aerial parts of echinops echinatus compositae  
   
نویسنده zaheer m. ,hussain n. ,rahman s. ,rehman s.-u.
منبع pakistan journal of scientific and industrial research series b: biological sciences - 2012 - دوره : 55 - شماره : 1 - صفحه:40 -45
چکیده    Present study was focused on anti irritant potential of a xerophytic weed,echinops echinatus. for this purpose,petroleum ether,chloroform and methanol extracts of various polarities from the aerial parts of e. echinatus were collected. five fractions i.e.,ee-1 to ee-5 were isolated from the chloroform extract of powdered plant by column and thin layer chromatography. the anti irritant potential of these fractions were evaluated on rabbit's skin. the anti irritant activity was evaluated from the healing mechanism on the abraded and irritated animal's skin. two fractions (ee-2 and ee-4) appeared to be the potent anti irritant than others.
کلیدواژه Abraded; Animal skin; Anti irritant activity; Chromatography; Echinops echinatus
آدرس applied chemistry research center,pcsir laboratories complex,shahrah-e-jalaluddin roomi, Pakistan, applied chemistry research center,pcsir laboratories complex,shahrah-e-jalaluddin roomi, Pakistan, applied chemistry research center,pcsir laboratories complex,shahrah-e-jalaluddin roomi, Pakistan, department of pharmacy,islamia university of bahawalpur, Pakistan
 
     
   
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