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Thrombolytic and antimicrobial activities of Andrographis paniculata - A preliminary investigation
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نویسنده
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al-amina md.m. ,uddin m.m.n. ,islam md.s. ,chowdhury m.i. ,shohel m.
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منبع
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pakistan journal of scientific and industrial research series b: biological sciences - 2014 - دوره : 57 - شماره : 2 - صفحه:76 -80
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چکیده
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An attempt has been made to investigate thrombolytic and antimicrobial activities of ethanolic extracts of andrographis paniculata whole plant. phytochemical constituents of a. paniculata were assessed by human erythrocyte and the results were compared with standard streptokinase (sk). moreover,the plant extracts were compared with the antibiotic kanamycin to investigate antibacterial activity against several microorganisms. glycosides,steroids,phenols,alkaloid and tannins were found in the ethanol extract of whole plant. crude ethanol extract (p<0.05) and soluble fraction of ethanol extract (p<0.05) have shown thrombolytic properties. crude ethanol extract,n-hexane soluble fractions and carbon tetrachloride soluble fraction of ethanol extract of the whole plant have shown antimicrobial activities against common gram positive and gram negative microorganisms. the results of current study justify thrombolytic and antimicrobial activities of a. paniculata.
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کلیدواژه
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Andrographis paniculata; Antimicrobial activity; Thrombolytic activity
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آدرس
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department of pharmaceutical sciences,north south university,bashundhara, Bangladesh, department of pharmacy,university of chittagong, Bangladesh, department of pharmacy,school of science and technology,manarat international university,mirpur, Bangladesh, department of pharmacy,school of science and technology,manarat international university,mirpur, Bangladesh, department of pharmaceutical sciences,north south university,bashundhara, Bangladesh
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Authors
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