Cyclic voltammetric studies of thymoquinone with iron (III)

Complexion of thymoquinone an active ingredient of nigella saliva,with fe(iii) has been analyzed using cyclic voltammetry. this electrochemical study was performed at glassy carbon as working electrode,platinum as auxiliary and saturated calomel as reference electrode. whole work was performed at 25±1 °c in aqueous medium using nacl as supporting electrolyte. present study reflects effects of scan rates,concentrations,ratios and successive cyclic scans on fe(iii)-thymoquinone complex. results revealed that the complex shows quasi-reversible electron transfer process. e° of complex was found to be 0.271± 0.030 v whereas diffusion coefficient was 9.178×10-5 cm2. the values of transfer coefficients,α and β were also determined. the value of a was found to be 0.786±0.01-0.923±0.02 whereas value of β was found in the range of 0.813±0.01-1.021±0.01. calibration curve method with linear regression line confirms that cyclic voltammetry can be used for quantification of fe(iii)-thymoquinone complex for pharmaceutical assay.