Role of trimetazidine (vestral MR ) in acute myocardial infarction

Introduction: the coronary artery disease is the leading cause of death in u.s.,europe and in developed countries. objectives: to assesses the clinical benefit of use of trimetazidine in acute mi along with thrombolytic therapy. 100 patients with acute mi were included in this study. subjects and methods: this study was carried out in the departments of medicine at sir ganga ram hospital and services hospital,lahore on 100 patients fulfilling the criteria for acute mi during the 1 year study period. results: one hundred patients were included in group i and group ii (50 patients each).in group -i,50 patients were treated with thrombolytic therapy i.e. streptokinase alone. in group- ii,50 patients were treated with streptokinase along with trimadizidine. these patients were followed up till six month and complications like arrhythmia,congestive cardiac failure,bleeding,re-infarction,angina and death were compared between two groups.