Bone marrow aspiration biopsy: Work-up of metastatic malignant disorders

Aims and objectives: this study has been conducted to find out bone marrow infiltration in different malignant disorders. metastases to bone marrow is a hallmark of human malignancies. metastatic tumors to bones are more common as compared to primary bone tumors and likelihood of bone metastases depends upon the type of primary tumor. tumors that commonly metastasize to the skeleton include those originating from lymph node,breast,lung,prostate,kidney and gastrointestinal tract. bone marrow aspiration and trephine biopsy is a useful tool for staging of patients with various malignant disorders. material and methods: this cross-sectional study included 100 patients with different malignancies. these patients were taken from oncology departments of shaikh zayed and mayo hospitals,lahore. bone marrow aspiration and trephine biopsy were performed on these patients. results: fifty six patients were male while forty four were female. in our study maximum number of patients with bone marrow infiltration were of carcinoma breast. other cases in the study included non-hodgkin's lymphoma,carcinoma prostate,carcinoma of the lung and carcinoma ovary.