Perinatal and maternal outcome associated with induction of labour

Objective: to describe the maternal risk factors and maternal and perinatal outcome associated with labour induction. design: a cross- sectional study setting: gynae unit iii sgrh,lahore,from july 2007- june 2010,a three years study. patients and methods: all patients admitted for labour induction through outpatient department as well as emergency were included in the study. main outcome measures: indication for induction of labour,method of induction,risk factors for induction,success rate of each method and maternal and perinatal outcomes. results: 5727 patients were admitted for induction of labour during the study period. the indications of labour induction were premature rupture of membranes (or 3.29,95% ci,2.90,3.73) prolonged pregnancy (or 4.15,95%ci 3.82,4.50) iugr,congenital anomaly or intrauterine deaths. the success rate of vaginal delivery was comparable for oxytocin and misoprostol with an overall success rate of 71.5% and c-section rate of 28.5%. induction of labour was more common in women over 35 years of age or 1.37,95% ci 1.14,1.65. maternal complications included increase need for uterotonic agents,instrumental delivery,higher rate of c-section,hysterectomy,icu admission,hospital stay of >7 days and increased need for consultant obstetricians and anesthetists. the adverse perinatal outcomes included low 5 minute apgar score,low birth weight (rr;0.9;95%ci:0.8-1.1) admission to neonatal icu,and delayed initiation of breast feeding and perinatal deaths (rr; 0.8; 95% ci: 0.6-1.2). conclusions: the prevalence of labour induction was 12.5% with a success rate of 71.5%,irrespective of the method used. the most frequent indication was premature rupture of membranes. induced labour is associated with poor maternal and perinatal outcome.