Assessment of lipid profile in pre-eclampsia

Objective: assessments of lipid profile in preeclampsia. design: a cross-sectional analytical study. place and duration of study: department of physiology,bmsi,jpmc karachi in collaboration with department of gynecology and obstetrics jpmc karachi. subjects and methods: study included 90 subjects distributed into three groups of 30 subjects each. 30 were apparently healthy subjects. 30 mild preeclamptic and 30 severely preeclamptic. clinical detailed were collected. fasting blood samples were drawn by adopting aseptic methods and serum was analyzed for lipid profile. results: among 90 screened subjects serum triglycerides in 30 normal subjects was (176.76 mg/d1),in 30 mild preeclamptic subjects showing (235.53mg/ldl),was highly significant as compare to normal. however 30 severe preeclamptic subjects show serum triglycerides 242.mg/dl as compare to normal. the difference in both groups were statistically highly significant as compare to normal. conclusion: concluded that lipid profile levels were elevated with preeclampsia which suggests that elevated circulating levels may be involved in pathogenesis of uteroplacental vascular disease associated with preeclampsia,which may be risk marker in pregnant women.