Pattern of congenital malformations and their neonatal outcome at Sheikh Zayed Medical College/Hospital Rahim Yar Khan

Objective: to highlight the pattern of congenital malformations in neonates admitted in a tertiary care nursery and to evaluate their outcome after treatment. study design: descriptive study. place & duration of study: department of pediatrics medicine & surgery,sheikh zayed medical college & hospital,rahim yar khan from january to december 2010. methodology: a total of 4270 patients were admitted in nursery. neonates with congenital malformations were diagnosed by clinical examination and by appropriate investigations. surgical intervention was done accordingly. results: out of 4270 patients admitted in nursery in one year,645 patients (15%) were diagnosed as having congenital malformations. 335 were male and 302 were female & 8 were having ambiguous genitalia. 45 neonates died pre-operatively,345 patients had surgery out of which 42 patients (12.1%) died in neonatal period,217 were advised surgery after neonatal period,and 38 patients refused surgery & were managed conservatively. conclusion: by improvement in antenatal,postnatal diagnosis,urgent referral to tertiary care center,early surgical intervention and intensive post operative neonatal care,most infants can be saved.