Comparison of analgesic effect of Ketorolac and Lidocaine in reduction of propofol induced pain

Objective: to compare the analgesic effect of ketoralac and lidocaine in attenuating propofol induced pain at the time of induction of general anaesthesia for surgical procedures. study design:-randomized controlled trials. place and duration of study:-department of anesthesiology services hospital,lahore from dec.2009 to june 2010. patient and method: study was conducted on two hundred patients irrespective of sex age range.18-50 years of asa class p1 and p2. result: total numbers of patients in study were,200.100 in group a (ketoralac and 100 in group b (lidocain). in group a,12 patients (12%) had no pain. in group b,62 (62%) had no pain. it is statistically highly significant (p< 1.00). mild pain in 18 patients (18%) was in group a and also mild pain in 18 patients (18%) in group b. it is statistically not significant (p 1.00). moderate pain in 14 patients (14%) in both groups a & b again statistically no significant. 56 patients (56 %) had severe pain in group a and only 6 (6%) in group b which was statistically highly significant. conclusion:- although both drugs lidoocain and ketorolac are effective in reducing propofol induced pain but lidocain is more effective than ketorolac in this regard.