Misoprostol for the purpose of midtrimester termination of pregnancy: A comparative study with prostaglandin F2 alpha with oxytocin infusion

Objective: to compare the efficacy of misoprostol verses prostaglandin f2 alpha with oxytocin usage in the medical management of termination of pregnancy due to presence of congenital anomalies incompatible to life or intrauterine fetal demise. design: comparative study place and duration of study: the present study was conducted in services hospital lahore between january2011 and march 2011. method: a total number of 50 patients of 18-40 years of the age were studied. these patients were randomly selected who presented to gynecology and obstetrics out door with mid trimester fetal or congenitally malformed fetus incompatible to life,conformed on ultrasonography. these women randomized to receive either intravaginal misoprostol or extraaminotic prostaglandin f2 alpha along with oxytocin for midtrimester termination of pregnancy. results: a comparative study was carried out which revealed that out of the 50 studied patients,the presenting age of misprostol treating group was 26.7 and age of pgf2 alpha oxytocin treating group was 25.0. gestation age of misprostol treating group was 23.6 and pgf2 alpha oxytocin treating group was 22.8. bishop score of misprostol treating group was (5.08 mean) and pgf2 alpha oxytocin treating group (5.2 mean). expulsion of fetus in misprostol treating group was 24(96%) and in pgf2 alpha oxytocin treating group 23(92%). evacuation need in misprostol treating group was 4(16%) and in pgf2 alpha oxytocin treating group 11(44%).