Total-cholesterol vs HDL-cholesterol

Niacin,a b vitamin,has long been used to increase high-density lipoprotein (hdl),the good cholesterol which helps sweep up low-density lipoprotein (ldl),or bad cholesterol,in bloodstream. boosting hdl level can be just as important as lowering ldl cholesterol. taking niacin,either by itself or along with other cholesterollowering medication helps to control serum total cholesterol level. the research study was conducted in jinnah hospital lahore from january 2010 to june 2010. it was single blind placebo-controlled research study. when 3 grams of niacin was used daily in divided doses in 50 hyperlipidemic patients for three months,it reduced ldl-cholesterol 19.59%,total serum cholesterol 19.10 % and hdl-cholesterol increased 17.37%. biostatistically changes in all parameters of lipid profile are highly significant. it was concluded from the research work that niacin increases good cholesterol (i.e.,hdl-cholesterol) and decreases bad cholesterol (i.e.,ldl-cholesterol) which results in making ldl-cholesterol/hdl-cholesterol ratio to lower margins/levels that is good indicator for prevention of heart diseases.