Efficacy of adipose tissue in fat graft tympanoplasty

Objectives: the objective of this study was to evaluate the success of using fat graft as a material intympanoplasty and to discuss its utilities,advantages and disadvantages. study design: retrospective descriptive study place and duration of study: this study was conducted in department of ent,fouji foundation hospital,lahore under counseling of professor azharhameed ent unit 1,mayo hospital associated with king edward medical university,lahore. it spanned over a period of two years from may 15,2009 to may 15,2011. material and method: 58 patients with dry central perforationsyndrome were evaluated preoperatively by detailed history,clinical examination and relevant investigations like examination under microscope,pure tone audiogram and x-ray of the temporal bone. results: all 58 patients were operated. in all 19 (32.75 %) of 58 male patients 100 % successful closure of perforation was achieved. while in 2 (3.44 %) female patient's grafts were rejected following infection. conclusion: fat graft tympanoplastyhas high graft take up rate and it cansurvive infection with respect to temporalis fascia graft.however the procedure cannot be done in patients with large perforations. moreover fat takes 6 to 9 months to resolve completely.