Clinicopathological pattern in 150 females presenting with benign and malignant ovarian tumors

Objective: to study the histological pattern of benign and malignant ovarian neoplasms. study design: a cross-sectional study. duration of study: two and half years. place of study: departments of pathology,fatima memorial hospital and arif laboratory,hameed latif hospital lahore. methods: the study consisted of 150 specimens of ovarian tumors,received fixed in 10% formalin. haematoxylin and eosin stained slides were examined to determine the histological type by who classification. results: majority of these tumors were benign (74%),border line tumors were <2% and malignant tumors were 24.33%. histologically the major categories were surface epithelial tumors 92 (61.33%),germ cell tumors 48 (32%) sex cord stromal tumors 9(6%) and metastatic adenocarcinoma 01 (0.66%). amongst malignant tumors,the most common category was malignant surface epithelial tumor (67.56%) followed by malignant germ cell tumors (24.32%). serous cystadenocarcinoma was the most common malignant ovarian tumor and 88% malignant surface tumors were seen in the 5th and 6th decades. all 9 malignant germ cell tumors (100%) occurred in patients below 30 years of age. serous cystadenoma was most common benign tumor (38.73%) followed by mature cystic teratoma (35.13%). benign ovarian tumors 60.36%(67/111) were seen in 3rd and 4th decades. conclusion: epithelial tumors are the commonest variety of ovarian tumors followed by germ cell tumors. there are minor differences from local and western studies.