Effect of mefloquine on eye

Objective: to study the effect of mefloquine on visual status. patients & methods: sixty nine confirmed cases on weekly mefloquine therapy (for malaria prophylaxis) for 01 year were included in the study. visual acuity,intraocular pressure (iop),anterior and dilated posterior segment examination and visual fields (vf) were carried out to determine the ophthalmic status. results: out of 69 patients,2 were found to have pain and mild blur in visual acuity. however none has disc,vf,fundus,and anterior or posterior segment retinal changes. mean age of subject was 43 years. 58 (84.05%) were males and 11 (15.94%) were females. conclusion: there seems to be no risk of visual loss after mefloquine therapy for 01 year. moreover further study is required to assess more longterm use risk.