To identify the role of C-reactive protein in predicting the response of thrombolytic therapy in acute myocardial infarction

Objectives: to identify the role of c-reactive protein in predicting the response of thrombolytic therapy in acute myocardial infarction. study design: cross sectional study. setting: department of medicine,nawaz sharif social security hospital lahore. duration of study: this study carried out from february 2011 to january 2012. subjects and methods: sixty patients were included in this study. information of patients like age,symptoms,myocardial infarction distribution,symptoms according their sex,thrombolytic therapy,correlation between crp-1 and time duration and crp-2 and time duration. results: the age range was 37-70 years,most common age group was 51-60 years,26(43%) patients. forty (67%) were males and 20(33%) were females. chest pain,sweating,dyspnea and vomiting were the main symptoms at presentation,among them chest pain and sweating were the most common,30(50%) patients. inferior wall mi was the most common,25(45%) patients. successful thrombolysis was seen in 39(65%) patients and 21(35%) patients failed to respond. there was significant correlation between duration of symptom onset and plasma crp levels (p value <0.05). conclusion: it is concluded that c-reactive protein has prognostic value for outcome of the disease in patients with acute myocardial infarction and plasma c-reactive protein begins to rise 4-6 hours after onset of symptoms in acute myocardial infarction.