Efficacy of streptokinase on st segment elevation MI in Diabetic and Non-Diabetic

Aims: to compare the efficacy of streptokinase on st segment elevation mi in diabetic and non-diabetic study design: it was a randomized clinical trial. duration: from may 2012 to june 2012. material and method: the patients of st segment elevation myocardial infarction were recruited from the department of cardiology,jinnah hospital,lahore. result: baseline characteristics of non-diabetic and diabetic myocardial infarction patients i.e. common age of the patients in both groups were similar and having no significant difference i.e. 49.43±4.27 in diabetic and 46.74±3.12 in non-diabetic group,82.5% were male in diabetic and 72.5% in non-diabetic group. comparison of efficacy of streptokinase on st segment elevation mi in diabetic and non-diabetic was recorded which shows 85% in non-diabetic and only 30% in diabetic patients. p value was calculated as 0.00. conclusion: in light of the present results we may conclude that the thrombolytic therapy is more effective in non-diabetics than diabetic subjects with stemi,however,more attention should be given to the diabetic individuals before administration of thrombolytic therapy.