Comparison of hydrogen peroxide and trichloracetic acid in recurrent oral aphthous ulceration minor

Objective: to compare the results of hydrogen peroxide and trichloracetic acid in patients with recurrent oral aphthous ulceration of minor type. study design: normative comparison study. setting: dhq teaching hospital and private clinics of the authors at kohat. study period: january 2010 to december 2010. patients and methods: clinically diagnosed 60 patients of recurrent oral aphthous ulceration of minor (roaum) were included in this study. patients were distributed into group a and b having 30 patients in each. group a having patients treated with 5% hydrogen peroxide and group b of patients treated with 20% trichloroacetic acid (tca). both the drugs were used by topical application to all the patients. all the cases were thoroughly evaluated after 6-days of treatment. reduced or abolished surrounding erythema,tenderness and tingling sensation were used as assessment criteria. results: out of total 60 patients of recurrent oral aphthous ulceration minor (roaum),there were 15 males (25%) and 45 females (75%) with male to female ratio of 1:3.the age range was 15-50 years where mean age was 35year. in group a,26 patients (86.6%) got the relief from sumptoms while in group b,only 7 patients (23.4%) went into relief.x2 was aplied to both groups.chi-square value was 0.66 for which p value is 0.4155 representing non significant results. presentation of surrounding erythema,tenderness and tingling sensation were found in almost all studied cases. conclusion: hydrogen peroxide 5% is a safe,cost effective,easily applicable agent in the treatment of recurrent oral aphthous ulceration minor (roaum) type .it is beneficial for such patients in our country.