Unfavorable effects of pre-eclampsia on the morphology of the placenta

Aim: to correlate the placental morphometric parameters with newborn weight between the two groups i.e. normal vs. patients of preeclampsia study design: case-control study place & duration of study: department of anatomy,sheikh zayed medical college,rahim yar khan incollaboration with departments of anatomy,pathology and obstetrics and gyanecology,quaid-e-azam medical college bahawalpur,from august 2011 to november 2012. results: one hundred human placentae,50 were from normal pregnant women as control and 50 from pregnancies complicated by preeclampsia were taken for this study. samples were grouped as group a and group b on the basis of absence and presence of preeclampsia respectively. all samples were studied morphologically. there was significant reduction in weight,diameter,thickness,volume and number of cotyledons of placenta in pre-eclamptic group. weight and diameter of placenta had significant positive correlation with the weight of newborn in both groups.