Sensitivity pattern among bacterial isolates in neonatal septicaemia in tertiary care hospital

Objective: to study the frequency of bacterial isolates of neonatal sepsis and their sensitivity pattern. patients and methods: it is a cross-sectional descriptive study and conducted at department of pathology,postgraduate medical institute lahore from january to december 2012. blood samples for culture and sensitivity were collected from clinically suspected cases of neonatal sepsis,using the standard technique of specimen collection .cultures were inoculated on blood and macconkey agar plates. antibiotic sensitivity test was done by modified kirby-bauer disc diffusion method according to the clinical and laboratory standards institutes guidelines 2011. results: total 478 blood culture bottles have been received from lgh during the study period,out of which 139(29%) were culture positive. gram-negative organisms recovered were 82% from the culture-positive cases. the predominant gram negative organisms were pseudomonas followed by enterobacter species. while gram positive organisms were only staphylococcus species which were 14%. candida species isolated was 4% from culture positive cases. conclusion: studies from different geographical area at different time should be compared to see the different pathogens and changing antibiotic susceptibility trend.