Obesity is a major risk factor of cardio vascular disease (CVD) in adults

Objective: to classify obesity into different classes on the basis of body bass index and waist hip ratio and to correlates all parameters of lipid profile with insulin hormones and insulin resistance value which causes diabetes and atherosclerotic cardiovascular diseases events. patients and methods: this descriptive study was carried out from free camp for obesity in clifton area and punjab colony,karachi from november 2010 to april 2011. overweight adults (20-40 years) were selected along with the history of xanthoma,yellow coloration of eyes,and high blood pressure and cardiac arrest. one hundred samples were taken for fasting blood sugar (fbs),lipid profile,insulin,insulin resistance (ir). the measurement of body mass index (bmi),and waist hip ratio and some biochemical parameters was measured by following the criteria of the national heart lung and blood institute. results: hundred patients were selected for the purposes of study. body mass index was increases in both adult male and female (m=31.27±1.2,f=31.3±0.27),and waist hip ratio was slightly increases in adult male (1.2±0.04) as compared to female (1.1±0.025).the statically analysis was carried out in all parameters of lipid profile in both male and female adult obese. in female obese cholesterol,(280.29±2.38),triglycerides [tg] ( (180.14±1.93and low-density lipoprotein [ldl] (178.95±1.58) was slightly increased,as compared with male obese i.e.,cholesterol (277.51±2.06),triglycerides (175.62±2.32),and low density lipoprotein (177.08±1.79),whereas high density lipoprotein (hdl) was slightly decreases in female obese (21.83±0.68) as compared with male obese cases (23.56±0.66). the analysis was carried out on the fasting blood sugar level. the fasting blood sugar level was high in the female obese (160.04±2.55) than male obese (151.96±2.32). the analysis was also applied on insulin level and insulin resistance. it was noted that there was slightly increase level of insulin in male (m= 5.820.24±) as compared with (f=5.77±0.25),whereas insulin resistance was also slightly increased in males (m=1.88±0.061) when compared with female. conclusion: triglycerides,low-density lipoprotein,high-density lipoprotein,fasting blood sugar,insulin and insulin resistance are a major risk factor of cardiovascular diseases in adults.