Sensitivity Pattern of Staphylococcus aureus isolates to commonly used antibiotics

Aim: to investigate the sensitivity pattern of staphylococcus aureus isolates obtained from clinical specimens including urine,and wound to commonly used antibiotics. methods: this prospective study was conducted from june 2010 to july 2011. clinical specimens including urine,wound swab were collected from the patients of orthopedic department of hayatabad medical complex peshawar with informed consent and was analyzed in pathology department of kabir medical college peshawar. the samples were cultured aerobically in blood agar and cystine lactose electrolyte deficient (cled) agar. the isolates were identified using motility test,colony morphology,gram staining and biochemical tests. the discs of amoxycillin,co-amoxiclav,cephradine,cefuroxime,sparfloxacin,meronem,tinem and linzolid were used. results: there were total 150 cases which contain 75 each of high urine sample and wound swab. there were 85 male patients and 65 female patients. in wound swab specimens,sensitivity pattern was; tinem (98.7%),linzolid (97.3%),meronem (94.7%),co-amoxiclav (93.3%),cephradine(90.7%),cefuroxime (86.7%),amoxycillin (82.7%) and sparfloxacin (80%). in urine specimen the s. aureus was sensitive to tinem (94.7%),meronem (93.3%),sparfloxacin (93.3%),linzolid (90.7%),cefuroxime (86.7%),co-amoxiclav (80%),amoxycillin (69.4%),cephradine conclusion: staphylococcus aureus in wound and urine culture almost always sensitive to tinem antibiotic. sensitivity to cephradine in wound culture is double that of urine culture.