Comparison of morphological changes in placentae from pre-eclamptic pregnancies and normal pregnancies

Aim: to assess the morphology of placenta from mothers having pre-eclampsia and to correlate with those from normal pregnancies. study design: study type; prospective study research design: case control study place of study: department of anatomy,basic medical sciences institute (bmsi),jinnah postgraduate medical centre (jpmc),karachi. methods: total of 50 placentae were collected,divided into two groups,control (group a) and preeclamptic (group b) groups. each group consisted of 25 placentae. all the placentae were observed for morphological features. results: in this study,shape of placenta showed no changes in both pre-eclamptic and control groups. preeclamptic placentae showed a highly significant decrease (p<0.001) in weight,diameter,thickness and number of cotyledons as compared to normal placentae. conclusion: the present study concluded that pre-eclampsia is associated with remarkable morphological changes in the placentae.