Uric acid levels in good controlled and poorly controlled diabetic patients

Background: diabetes mellitus is a metabolic disorder which is characterized by hyperglycemia. prevalence of diabetes is high ranging from 7.6 to 11% in pakistan. diabetes can affect many different organs in the body and can lead to various complications. glycosylated hemoglobin (hba1c) is the most vital tool to monitor glycemic control. desirable value for hba1c is below 7.00. the association between the blood glucose and the serum uric acid levels has been known for quite some time. some studies have demonstrated the role of ua in the progression of pre diabetes to dia betes. methods: this cross sectional study was conducted in the laboratory of ghurki trust teaching hospital,lahore. a total of 158 diabetic patients were included. uric acid levels were performed by colorimetric method (uricase) on fully automated chemistry analyzer. hba1c was performed by high performance liquid chromatography (hplc). data was analysis by using spss. results: 63.9% population was female and 36.1% population was male. mean age of the study population was 48.14±11.29 years (range 2479 years). two groups of the study subjects were formulated on the basis of hba1c results. the participants of the study having hba1c of less than or equal to 7% were included in good control group while the study participants having hba1c value of equal or greater than 7% were assigned in poor control group. the difference of means between good control and poor control group was statistically non significant with a pvalue of 0.694. conclusion: the present study concluded that there is no significant association of hba1c levels with serum uric acid levels in our population. uric acid should only be requested in case of patient presenting with symptoms of hyperuricemia.