Misoprostol vaginal pessary versus dinoproston vaginal gel in induction of labour

Aim: to compare misoprostol vaginal pessary with dinoprostone vaginal gel to know which of these two agents is more safe and effective for induction of labour method: a interventional quasi experimental study was carried out in sir ganga ram hospital,lahore over a period of six months from 13th feb,2007 to 13th aug,2007. a total of 100 women at 37-42 months of gestation were assigned into two groups. fifty women in group a received dinoprostone vaginal gel and 50 women in group b received misoprostol vaginal pessary. results: 68% in group a and 87% in group b deliver within 24 hours of induction. 60% patients in group a and 56% in group b had spontaneous vaginal delivery,64% patients in group a and 66% patients in group b required oxytocin for augmentation. nausea and vomiting was observed in 8% patients in group-b with no case reported in group a. fetal and maternal complications were also comparable in both groups. overall babies delivered with good apgar score at 1 & 5 minute interval. conclusion: both dinoprostone vaginal gel and misoprostol vaginal pessary appears to be equally safe and effective for induction of labour.