Frequency of ATT induced hepatitis in newly diagnosed pulmonary TB patients

Aim: to determine the frequency of att induced hepatitis in newly diagnosed pulmonary tb patients.methods: this descriptive,cross-sectional study was conducted at department of pulmonology jinnah hospital lahore from august 2013 to february 2014. total 95 newly diagnosed pulmonary tb patients were included in this study. baseline lfts including alt,ast,and bilirubin were done in every patient at time of induction and repeated at one month follow up. data was analyzed by using spss 16.results: mean age of the patients was 37.95 ± 14.46. among the participants males were 51(53.7%) and females were 44(46.3%). out of 95 patients,34(35.8%) had alt and ast derangements while 35(36.8%) had hyperbilirubinemia.conclusion: att induced hepatitis is a frequent complication in newly diagnosed cases of pulmonary tuberculosis. so,all patients put on att must be followed up for at least the initial month. the patients and the doctors have to be well-educated about the adverse effects of the att,its early recognition and management. © 2014 pakistan journal of medical and health sciences. all rights reserved.