Levels of glycated albumin and C-reactive protein as risk markers of coronary artery disease in type-2 diabetics

Aim: to determine the clinical usefulness of glycated albumin and hs-crp levels for predicting cad using logistic regression model in patients with type-2 diabetes methods: the cross-sectional study was conducted in the department of cardiology and pmrc centre nhrc,szm complex lahore from november 2011 to august 2012 with the assessment of ga and hs-crp levels was conducted in relation to the lumen narrowing levels amongst 90 subjects who were undergoing coronary angiography. study participants with < 30% lumen diameter narrowing were considered normal (group 1) whereas with lumen diameter 30-50% were considered mild cad (group ii),with 51-70% moderate cad (group iii) and greater than 70% severe cad (group iv). results: the association between glycated albumin levels,hs-crp and lumen narrowing diameter was found significant in all groups by applying anova (p<0.01). the post hoc tukey's test also showed significant relationship between all groups (p<0.01) except for hs crp between group iii and group iv (p 0.857). conclusion: both glycated albumin and hs-crp tests can be used to assess the levels of risk for cad with type-2 diabetes and other accompanying risk factors.