Efficacy of intra-peritoneal bupivacaine for analgesia in early post-operative period after laparoscopic cholecystectomy

Aim: to compare the efficacy of intra-peritoneal bupivacaine (25%) in early post-operative period after laproscopic cholecystectomy with a control group. study design: randomized control trial. method: 120 patients undergoing for laparoscopic cholecystectomy were included and divided into two equal groups b and c by using random number table. each group comprised of 60 patients. in group 'c' no intra-peritoneal bupivacaine was used. in group 'b' 20 ml of (.25%) bupivacaine was instilled in the right sub-diaphragmatic space and at gall bladder bed. results: post-operative mean abdominal pain score on vas in both groups on different intervals was calculated and recorded 1.34±0.43 (cm) in group b and 2.54±0.26 (cm) in group c at 0 hours,2.11±0.32 (cm) in group b and 2.98±1.05 (cm) in group c at 2 hours,2.98±1.05 (cm) in group b and 3.24±0.84 (cm) in group c at 4 hours while 3.13±1.21 (cm) in group b and 4.59±1.32 (cm) in group c at 6 hour were recorded. comparison of efficacy in both groups was recorded which reveals 22(36.67%) in group b and 4(6.67%) in group c while 38(63.33%) group b and 56(93.33%) in group c. conclusion: intra-peritoneal bupivacaine infiltration is an effective method for relief of post operative pain in laproscopic cholecystectomy.