Transdermal nitroglycerine in management of preterm Labour

Aim: to estimate the prolongation of gestation following transdermal nitroglycerine and to assess the changes in maternal arterial pressure before and after administering glyceryl trinitrate patch. methods: this is a quasi experimental study carried out in the department of obstetrics and gynaecology,divisional headquarter teaching hospital,mirpur azad kashmir from january 2014 to december 2014. fifty patients of all parity between 24-37 weeks of gestation were included and transdermal nitroglycerine applied 10mg/24 hours to see its efficacy and maternal and foetal effects. results: eight (16%) patients gestation prolonged less than 24 hours,6 (12%) patients had prolongation of gestation between 24-48 hours. twelve (24%) patients gestation was prolonged 48 hours to one week and in 24(48%) gestation prolonged above 1 week of which 6 patients reached till 37 weeks. no change in maternal blood pressure or pulse noted.