Deranged levels of renal parameters after using heavy metal Kushta of copper in diet of albino rats

Aim: to evaluate the effects of copper preparations of kushta on renal parameters. this study was conducted from 14th of may 2013 to 30th of november 2013 in pathology department of university of health sciences lahore and it was an experimental study. method: thirty albino rats were selected and divided into three groups. the control group a was fed on standard pellet rodent diet and tap water. the experimental group b was fed single dose of copper preparation of kushta (0.15mg/kg of body weight) for 18 weeks while experimental group c was fed double dose of copper preparation of kushta (0.30mg/kg of body weight) for 18 weeks. renal parameters were calculated once at the start of experiment and then after every 6 weeks up to 18 weeks. results: results showed that renal parameters in terms of serum creatinine level and proteinuria were deranged evident on biochemical analysis. when the control group a on normal diet was compared with the experimental group b and c,statistically significant difference (p<0.05) was noticed in terms of renal parameters. conclusion: it is therefore concluded that copper preparations of kushta deranged renal parameters in terms of serum creatinine levels and proteinuria.