Comparison of success rate of external dacryocystorhinostomy with and without mitomycin-c in patients of chronic dacryo-cystitis

Aim: to compare the efficacy of external dacryocystorhinostomy with and without intraoperative application of mitomycin-c in patients with chronic dacryocystitis. method: this randomized controlled trial was conduct at out patient department of ophthalmology,king fahad armed forces hospital,jeddah from march 2013 to february 2014. total 200 patients were enrolled. patients were randomly divided into two groups a & b.patients who had undergone external dacryocystorhinostomy,both male or female with age from 20 year to 70 years were included in present study results: success rate surgical procedure in group a was 96% and in group b was 85%. significant (p=0.014) difference between the success rate was seen between the both groups. female predominance was seen in both study groups. conclusion: external dacryocystorhinostomy with intraoperative mitomycin-c is more efficacious than external dacryocystorhinostomy without mitomycin-c.