Serum adiponectin and insulin levels in asymptomatic offspring's of patients with type 2 diabetes

Aim: to measure and compare the adiponectin and insulin levels of asymptomatic offspring of type 2 diabetic patients with asymptomatic offspring of non-diabetics. study design: case control study. setting: pathology department pgmi,lahore and diagnostic laboratory of uvas,lahore. period: nine months. methodology: healthy non diabetic offspring of diagnosed patients with type 2 diabetes mellitus attending the medical departments of lgh lahore,both male and female below 30 years of age,documented by normal fasting blood glucose level and not having any symptom of diabetes were included. results: in this study,adiponectin and insulin were measured by elisa technique in 100 subjects. mean±sd of adiponectin in control group was 5.20±2.23 and in study group was 4.38±1.38 having non-significant difference having p value 0.14. mean±sd of insulin in control group was 16.80± 4.09 and in study group was 18.40±13.32 having non-significant difference having p value 0.098. conclusions: insulin levels were significantly lower in control group as compared to asymptomatic offspring of patients having t2dm. the adiponectin levels were slightly lower in asymptomatic offspring of patients having t2dm as compared to the control group; these slight differences were not statistically significant. there was slight negative correlation between serum adiponectin levels and insulin levels which was statistically not significant.