Antibiotic resistance pattern of uropathogen in patient with Chronic Kidney Disease

Background: chronic kidney disease is one of the most common problems in southern punjab. on average 20 patients presented in outpatient department daily. most of this patient suffered from diabetes mellitus and other chronic disease like hypertension. now around half of patients belong to young age. repeated urinary tract infection is one of the leading causes of rapid deterioration of renal function. so it is important to study the resistance pattern of uropathogens. aim: to study the frequency of antibiotic resistance of uropathogens in ch. kidney disease patients. place of study: nephrology department,multan medical and dental college,multan. methods:two hundred and twenty patients with chronic kidney disease meeting the inclusion and exclusion criteria and attending the outpatient department and inpatient were included in the study after taking informed consent. every patient was evaluated for presence of uropathogens resistance against antibiotic in their urine specimen. results:in our study number of uropathogens identified among these e. coli was the predominant isolate making up 63.6% and this was followed by klebsela 18%.these uropathogens found to be resistant to multiple drugs and resistance reached upto 90% for certain drugs. conclusion:multidrug resistant uropathogens are common in patients of chronic kidney disease.